Which symptom is NOT associated with beta-blocker overdose?

The symptom of high blood pressure is not associated with beta-blocker overdose because beta-blockers primarily function to decrease heart rate and lower blood pressure. In the case of an overdose, the expected physiological response includes bradycardia (heart rate below 50), hypotension (low blood pressure), and various symptoms related to reduced cardiac output.

High blood pressure is contrary to the effects of beta-blockers, which block the beta-adrenergic receptors, leading to decreased cardiac contractility and heart rate, ultimately resulting in lower blood pressure. In an overdose scenario, the excessive blockade can further amplify these effects, leading to more pronounced hypotension rather than hypertension.

Therefore, understanding the pharmacological action of beta-blockers clarifies why high blood pressure is not a symptom of overdose; instead, the symptoms typically align with the drug's intended effects of reducing heart rate and blood pressure.