Which medication belongs to the benzothiazepines classification?

The medication that belongs to the benzothiazepines classification is diltiazem. Benzothiazepines are a subset of calcium channel blockers, which are primarily used to treat hypertension and various cardiovascular conditions.

Diltiazem works by inhibiting the influx of calcium ions during depolarization of cardiac and vascular smooth muscle, leading to vasodilation, decreased heart rate, and reduced myocardial contractility. This mechanism of action is particularly effective in managing angina, controlling heart rate in atrial fibrillation, and lowering blood pressure.

While the other medications listed—amlodipine, nifedipine, and verapamil—are also calcium channel blockers, they fall into different classifications. Amlodipine and nifedipine are dihydropyridines, which primarily affect vascular smooth muscle and are often used for their potent vasodilatory effects. Verapamil, on the other hand, is a phenylalkylamine and has a more significant effect on the heart and is commonly used for rate control in arrhythmias. Therefore, diltiazem is distinguished from these others by its unique classification as a benzothiazepine, highlighting its specific pharmacological profile and clinical applications.