When atorvastatin is prescribed, what laboratory values should be assessed?

When atorvastatin is prescribed, it is essential to assess hepatic enzymes because atorvastatin, like other statins, can affect liver function. This medication is metabolized by the liver and has been associated with liver enzyme elevations in some patients. Monitoring hepatic enzymes helps to identify any potential hepatotoxic effects early in the treatment process.

Regular assessment of liver function tests, specifically alanine aminotransferase (ALT) and aspartate aminotransferase (AST), is recommended before initiating therapy and periodically thereafter, particularly if symptoms or signs suggestive of liver issues occur. This ensures that any adverse effects on liver function can be addressed promptly and the medication adjusted as necessary to maintain patient safety.

Monitoring other laboratory values, such as blood glucose levels or thyroid function tests, while important in specific contexts or for certain patients, are not directly related to the mechanism of action or the primary safety profile of atorvastatin. Similarly, assessing serum electrolytes is not a routine necessity when starting atorvastatin, as the primary concern lies with the liver function in this scenario.