What is the route of administration for sacubitril/valsartan?

Sacubitril/valsartan is an oral medication, commonly prescribed for heart failure management. When administered orally, the drug is absorbed through the gastrointestinal tract, allowing it to reach systemic circulation effectively. This route is favored because it is convenient for patients and enables consistent dosing. Oral medications generally allow for a smoother pharmacokinetic profile and easier adjustment of dosages compared to alternatives like intravenous or subcutaneous routes. With sacubitril/valsartan specifically, the formulation is designed for effective absorption and therapeutic efficacy when taken by mouth, contributing to its role in treating chronic heart failure and improving outcomes for the patient population.