What benefit does an ACE inhibitor have on heart function after a myocardial infarction?

The benefit of an ACE inhibitor on heart function after a myocardial infarction primarily lies in its ability to reduce systemic vascular resistance. By inhibiting the angiotensin-converting enzyme, these medications lead to decreased levels of angiotensin II. This reduction results in the dilation of blood vessels, which lowers the overall resistance that the heart must work against to pump blood. As a consequence, there is a decrease in the workload of the heart, which is particularly beneficial following a myocardial infarction, where the heart muscle may be compromised.

This decrease in systemic vascular resistance not only helps improve cardiac output but also contributes to better perfusion of the myocardium, thus facilitating healing and recovery. Furthermore, by alleviating stress on the heart, ACE inhibitors can enhance overall cardiac function and reduce the risk of subsequent heart failure and other complications.