Before administering sacubitril/valsartan, which medication information should be discussed with the healthcare provider?

The choice revolves around the interaction between sacubitril/valsartan and certain medications. Sacubitril/valsartan is an angiotensin receptor neprilysin inhibitor (ARNI) used primarily for heart failure. When discussing medication information with a healthcare provider, it's crucial to highlight the use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) prior to starting sacubitril/valsartan.

Lisinopril is an ACE inhibitor, and its concurrent use with sacubitril can lead to a significant risk of angioedema, hypotension, and renal impairment. Therefore, it's essential to inform the healthcare provider of being on lisinopril because it may require a reassessment of the current treatment regimen to ensure patient safety before initiating sacubitril/valsartan therapy.

The other medications mentioned—atorvastatin, aspirin, and warfarin—do not have the same level of concern for direct interaction or contraindication when beginning treatment with sacubitril/valsartan compared to lisinopril. Thus, the focus on lisinopril is crucial for a safe and effective therapeutic plan.