A client taking niacin for hypercholesterolemia experiences facial redness and tingling. What is the nurse's best response?

The best response in this scenario is that facial redness and tingling are common side effects of niacin. Niacin, also known as vitamin B3, is often used to help lower cholesterol levels, but one of its well-known effects is causing vasodilation, which can lead to flushing and a tingling sensation, especially upon initiation of therapy or when doses are increased. This physiological response is typically not harmful and can be managed by taking the medication with food or using an extended-release formulation. Understanding that this reaction is a normal response to niacin helps alleviate any anxiety the client may have about experiencing these sensations and reinforces the importance of continuing the medication as prescribed unless otherwise advised by a healthcare provider. Acknowledging the side effect rather than suggesting immediate cessation or an allergic reaction promotes an informed approach to managing expected reactions to the treatment.