What should the nurse teach a client taking fenofibrate and warfarin?

When a client is taking fenofibrate alongside warfarin, it is essential to monitor their prothrombin time more frequently because fenofibrate can affect the metabolism of warfarin. Fenofibrate is known to potentially enhance the anticoagulant effects of warfarin, leading to an increased risk of bleeding. Therefore, increased monitoring helps ensure that the INR (International Normalized Ratio) remains within the desired therapeutic range, allowing for timely adjustments to the warfarin dosage as needed. This is crucial for maintaining patient safety and preventing any complications related to anticoagulation therapy.

While there are other relevant dietary and lifestyle considerations for patients on these medications, the critical teaching point in this scenario focuses on the need for more frequent blood testing to manage the interaction between fenofibrate and warfarin effectively.