In which scenario should atorvastatin be immediately discontinued?

Atorvastatin should be immediately discontinued in the scenario of muscle pain and elevated liver enzymes because these symptoms can indicate serious conditions such as rhabdomyolysis or hepatotoxicity. Muscle pain, especially if it is severe or accompanied by weakness, may signal the breakdown of muscle tissue (rhabdomyolysis), which can lead to kidney damage. Elevated liver enzymes suggest potential liver injury, which can be worsened by continued use of the medication. Discontinuing atorvastatin in this case is crucial to prevent further harm to the muscles and liver, allowing for assessment and appropriate management of these adverse effects.

Other scenarios, like mild headaches, a rash, or minor digestive upset may warrant close monitoring or a doctor's consultation but do not typically necessitate an immediate stop in atorvastatin therapy unless they are accompanied by more severe symptoms or if the healthcare provider advises otherwise.